1. (

• worsen ,
• aggravate ,
• exacerbate ,
• exasperate

) make worse; "This drug aggravates the pain" ;

2. (

• exacerbate ,
• exasperate ,
• aggravate

) exasperate or irritate ;

1. (

• aggravating ,
• exacerbating ,
• exasperating

) making worse ;