1. (

• derangement ,
• mental_unsoundness ,
• unbalance ,

) a state of mental disturbance and disorientation ;

2. (

• upset ,
• derangement ,
• overthrow ,

) the act of disturbing the mind or body; "his carelessness could have caused an ecological upset"; "she was unprepared for this sudden overthrow of their normal way of living" ;